Arsenal fear Rob Holding has suffered a season-ending cruciate ligament injury.

The central defender suffered a serious knee injury in the 2-2 draw at Manchester United on Wednesday.

Holding has been undergoing numerous tests to determine the extent of the injury. But there is real concern that Holding could have damaged his cruciate. 

Arsenal are still to confirm the extent of the injury and will hope for positive news in the next 24 hours.

Manager Unai Emery fears Holding faces a lengthy spell on the sidelines. He said on Thursday: ‘The first news is not good.’

Midfielder Aaron Ramsey (ankle) will be monitored before Saturday’s Premier League clash with Huddersfield, which Mesut Ozil is expected to miss with a back problem.

Emery added: ‘He had back ache and now he’s working with one physio. We’re going to look when he can come with us.’

Those players not involved at Old Trafford trained on Thursday morning and Laurent Koscielny could come into the matchday squad, after twice playing for Arsenal’s Under 23s, either on Saturday or next week against Qarabag in the Europa League.

Emery said: ‘The 18 can be for Saturday and also we are doing one plan with him, maybe he can play against Qarabag.

‘He’s working with us every day in training and playing in the Under-23s with good feeling. The next step, I think, is with us.’